Wayne J Fairbrother: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, Andrew J, Leverson, Joel D, Boghaert, Erwin R, Ackler, Scott L, Catron, Nathaniel D, Chen, Jun, Dayton, Brian D, Ding, Hong, Enschede, Sari H, Fairbrother, Wayne J, Huang, David C S, Hymowitz,

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

2

Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Fairbrother, Wayne J., Christinger, Hans W., Cochran, Andrea G., Fuh, Germaine, Keenan, Christopher J., Quan, Clifford, Shriver, Stephanie K., Tom, Jeffrey Y. K., Wells, James A., Cunningham, Brian C.

Journal:

Year:

1998

Language:

english

File:

PDF, 459 KB

english, 1998

3

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Ashkenazi, Avi, Fairbrother, Wayne J., Leverson, Joel D., Souers, Andrew J.

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 752 KB

english, 2017

4

Designer Proteins to Trigger Cell Death

Fairbrother, Wayne J., Ashkenazi, Avi

Journal:

Year:

2014

Language:

english

File:

PDF, 320 KB

english, 2014

5

NMR analysis of site-specific mutants of yeast phosphoglycerate kinase : An investigation of the triose-binding site

Wayne J. FAIRBROTHER, Philip A. WALKER, Philippe MINARD, Jennifer A. LITTLECHILD, Herman C. WATSON, Robert J. P. WILLIAMS

Journal:

Year:

1989

Language:

english

File:

PDF, 1.01 MB

english, 1989

6

Protein NMR Techniques . David G. Reid

Fairbrother, Wayne J.

Journal:

Quarterly Review of Biology

Year:

1999

Language:

english

File:

PDF, 64 KB

english, 1999

7

Identification of a Novel Death Domain-Containing Adaptor Molecule for Ectodysplasin-A Receptor that Is Mutated in crinkled Mice

Minhong Yan, Zemin Zhang, John Ridgway Brady, Sarah Schilbach, Wayne J. Fairbrother, Vishva M. Dixit

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 281 KB

english, 2002

8

Structure-guided design of a selective BCL-XL inhibitor

Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, P

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

9

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

Wiesmann, Christian, Katschke, Kenneth J., Yin, JianPing, Helmy, Karim Y., Steffek, Micah, Fairbrother, Wayne J., McCallum, Scott A., Embuscado, Lizette, DeForge, Laura, Hass, Philip E.

Journal:

Year:

2006

Language:

english

File:

PDF, 926 KB

english, 2006

10

Solution structure of the heparin-binding domain of vascular endothelial growth factor

Wayne J Fairbrother, Mark A Champe, Hans W Christinger, Bruce A Keyt, Melissa A Starovasnik

Journal:

Year:

1998

Language:

english

File:

PDF, 273 KB

english, 1998

11

Solution Structure of the E-Domain of Staphylococcal Protein A ‡

Starovasnik, Melissa A., Skelton, Nicholas J., O'Connell, Mark P., Kelley, Robert F., Reilly, Dorothea, Fairbrother, Wayne J.

Journal:

Year:

1996

Language:

english

File:

PDF, 758 KB

english, 1996

12

Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity

Sleebs, Brad E., Czabotar, Peter E., Fairbrother, Wayne J., Fairlie, W. Douglas, Flygare, John A., Huang, David C. S., Kersten, Wilhelmus J. A., Koehler, Michael F. T., Lessene, Guillaume, Lowes, Kym,

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.81 MB

english, 2011

13

Further Insights into the Effects of Pre-organizing the BimBH3 Helix

Okamoto, Toru, Segal, David, Zobel, Kerry, Fedorova, Anna, Yang, Hong, Fairbrother, Wayne J., Huang, David C. S., Smith, Brian J., Deshayes, Kurt, Czabotar, Peter E.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 209 KB

english, 2014

14

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1H and natural abundance 13C NMR spectroscopy

Neil E. Jacobsen, Wayne J. Fairbrother, Charlotte R. Kensil, Amy Lim, Deborah A. Wheeler, Michael F. Powell

Journal:

Carbohydrate Research

Year:

1996

Language:

english

File:

PDF, 670 KB

english, 1996

15

Characterization of the Binding Interface between the E-Domain of Staphylococcal Protein A and an Antibody Fv-Fragment †

Meininger, David P., Rance, Mark, Starovasnik, Melissa A., Fairbrother, Wayne J., Skelton, Nicholas J.

Journal:

Year:

2000

Language:

english

File:

PDF, 668 KB

english, 2000

16

Mapping of the binding interfaces of the proteins of the bacterial phosphotransferase system, HPr and IIAglc

Chen, Yuan, Reizer, Jonathan, Saier, Milton H., Fairbrother, Wayne J., Wright, Peter E.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.18 MB

english, 1993

17

NMR assignments of the human cytokine interleukin-33

Andreas Lingel, Wayne J. Fairbrother

Journal:

Biomolecular NMR Assignments

Year:

2009

Language:

english

File:

PDF, 832 KB

english, 2009

18

One- and two-dimensional NMR studies of yeast phosphoglycerate kinase

Wayne J. FAIRBROTHER, Derrick BOWEN, Len HALL, Robert J. P. WILLIAMS

Journal:

Year:

1989

Language:

english

File:

PDF, 948 KB

english, 1989

19

Protein NMR Techniquesby David G. Reid

Review by: Wayne J. Fairbrother

Journal:

Quarterly Review of Biology

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

20

Evaluation of Assay Technologies for the Identification of Protein–Peptide Interaction Antagonists

Kadkhodayan, Saloumeh, Elliott, Linda O., Mausisa, Grace, Wallweber, Heidi Ackerly, Deshayes, Kurt, Feng, Bainian, Fairbrother, Wayne J.

Journal:

Assay and Drug Development Technologies

Year:

2007

Language:

english

File:

PDF, 352 KB

english, 2007

21

Internal Motions Prime cIAP1 for Rapid Activation

Phillips, Aaron H., Schoeffler, Allyn J., Matsui, Tsutomu, Weiss, Thomas, Dueber, Erin C., Fairbrother, Wayne J.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

22

Design, Synthesis, and Biological Activity of a Potent Smac Mimetic That Sensitizes Cancer Cells to Apoptosis by Antagonizing IAPs

Zobel, Kerry, Wang, Lan, Varfolomeev, Eugene, Franklin, Matthew C., Elliott, Linda O., Wallweber, Heidi J. A., Okawa, David C., Flygare, John A., Vucic, Domagoj, Fairbrother, Wayne J., Deshayes, Kurt

Journal:

ACS Chemical Biology

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

23

Anion binding study of yeast phosphoglycerate kinase by nuclear magnetic resonance and site-specific mutagenesis

FAIRBROTHER, WAYNE J., HALL, LEN, LITTLECHILD, JENNIFER A., MINARD, PHILLIPE, WATSON, HERMAN C., WILLIAMS, ROBERT J. P.

Journal:

Biochemical Society Transactions

Year:

1987

Language:

english

File:

PDF, 247 KB

english, 1987

24

A Reinvestigation of a Synthetic Peptide (TrPepz) Designed to Mimic Trypsin

James A. Wells, Wayne J. Fairbrother, Jacek Otlewski, Michael Laskowski, Jr. and John Burnier

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.00 MB

english, 1994

25

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 872 KB

english, 2010

26

1H assignment and secondary structure determination of human melanoma growth stimulating activity (MGSA) by NMR spectroscopy

Wayne J. Fairbrother, Dorothea Reilly, Timothy Colby, Richard Horuk

Journal:

Year:

1993

Language:

english

File:

PDF, 491 KB

english, 1993

27

High-Resolution Solution Structure of the EGF-like Domain of Heregulin-α ‡

Jacobsen, Neil E., Abadi, Nasrin, Sliwkowski, Mark X., Reilly, Dorothea, Skelton, Nicholas J., Fairbrother, Wayne J.

Journal:

Year:

1996

Language:

english

File:

PDF, 805 KB

english, 1996

28

Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity

Edosada, Conrad Yap, Quan, Clifford, Wiesmann, Christian, Tran, Thuy, Sutherlin, Dan, Reynolds, Mark, Elliott, J. Michael, Raab, Helga, Fairbrother, Wayne, Wolf, Beni B.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

29

Compounds in the droplets of the orb spider's viscid spiral

Vollrath, Fritz, Fairbrother, Wayne J., Williams, Robert J. P., Tillinghast, Edward K., Bernstein, David T., Gallagher, Kathleen S., Townley, Mark A.

Journal:

Year:

1990

File:

PDF, 621 KB

1990

30

Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain

Melissa A. Starovasnik, Mark P. O'Connell, Wayne J. Fairbrother, Robert F. Kelley

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 1.70 MB

english, 1999

31

Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors—Insight into Heterotrimeric IL-1 Signaling Complexes

Andreas Lingel, Thomas M. Weiss, Marc Niebuhr, Borlan Pan, Brent A. Appleton, Christian Wiesmann, J. Fernando Bazan, Wayne J. Fairbrother

Journal:

Year:

2009

Language:

english

File:

PDF, 1.68 MB

english, 2009

32

Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor

Borlan Pan, Bing Li, Stephen J Russell, Jeffrey Y.K Tom, Andrea G Cochran, Wayne J Fairbrother

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 905 KB

english, 2002

33

An NMR analysis of the binding of inhibitors to yeast phosphoglycerate kinase

Helena A. BOYLE, Wayne J. FAIRBROTHER, Robert J. P. WILLIAMS

Journal:

Year:

1989

Language:

english

File:

PDF, 844 KB

english, 1989

34

Small-molecule pan-IAP antagonists: a patent review

Flygare, John A, Fairbrother, Wayne J

Journal:

Expert Opinion on Therapeutic Patents

Year:

2010

Language:

english

File:

PDF, 474 KB

english, 2010

35

Crystal Structure of the Complex between VEGF and a Receptor-Blocking Peptide ‡

Wiesmann, Christian, Christinger, Hans W., Cochran, Andrea G., Cunningham, Brian C., Fairbrother, Wayne J., Keenan, Christopher J., Meng, Gloria, de Vos, Abraham M.

Journal:

Year:

1998

Language:

english

File:

PDF, 223 KB

english, 1998

36

SMAC Negatively Regulates the Anti-apoptotic Activity of Melanoma Inhibitor of Apoptosis (ML-IAP)

Vucic, Domagoj, Deshayes, Kurt, Ackerly, Heidi, Pisabarro, Maria Teresa, Kadkhodayan, Saloumeh, Fairbrother, Wayne J., Dixit, Vishva M.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 740 KB

english, 2002

37

Probing the 3-phosphoglycerate-binding site of yeast phosphoglycerate kinase using site-specific mutants and 1 H nuclear magnetic resonance spectroscopy

FAIRBROTHER, WAYNE J., HALL, LEN, LITTLECHILD, JENNIFER A., WALKER, PHILIP A., WATSON, HERMAN C., WILLIAMS, ROBERT J. P.

Journal:

Biochemical Society Transactions

Year:

1988

Language:

english

File:

PDF, 216 KB

english, 1988

38

Heterobifunctional molecules induce dephosphorylation of kinases – a proof of concept study

Yamazoe, Sayumi, Tom, Jeffrey, Fu, Yue, Wu, Wenqiong, Zeng, Liang, Sun, Changlei, Liu, Qi, Lin, Jie, Lin, Kui, Fairbrother, Wayne J, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 465 KB

2019

39

Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2-Pro1-cleaving specificity

Conrad Yap Edosada, Clifford Quan, Thuy Tran, Victoria Pham, Christian Wiesmann, Wayne Fairbrother, Beni B. Wolf

Journal:

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

40

N.m.r. structural studies on the tyrosine kinase domain of the human insulin receptor

ATKINSON, ROBERT A., FAIRBROTHER, WAYNE J., LEVINE, BARRY A., TAVARÈ, JEREMY, CLACK, BEA, ELLIS, LELAND

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 147 KB

english, 1989

41

Exploring Protein—Protein Interactions with Phage Display

Sachdev S. Sidhu, Wayne J. Fairbrother, Kurt Deshayes

Journal:

Year:

2003

File:

PDF, 51 KB

2003

42

An NMR study of anion binding to yeast phosphoglycerate kinase

Wayne J. FAIRBROTHER, Heidi C. GRAHAM, Robert J. P. WILLIAMS

Journal:

Year:

1990

Language:

english

File:

PDF, 874 KB

english, 1990

43

Growth Hormone Secretagogues: Characterization, Efficacy, and Minimal Bioactive Conformation

Robert S. McDowell, Kathleen A. Elias, Mark S. Stanley, Daniel J. Burdick, John P. Burnier, Kathryn S. Chan, Wayne J. Fairbrother, R. Glenn Hammonds, Gladys S.Ingle, Neil E. Jacobsen, Deborah L. Morte

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 895 KB

english, 1995

44

Cover Picture: ChemBioChem 1/2003

Sachdev S. Sidhu, Wayne J. Fairbrother, Kurt Deshayes

Journal:

Year:

2003

File:

PDF, 19 KB

2003

45

Letters to the Editor1H,13C, and15N resonance assignments of SAP18

Scott A. McCallum, JianPing Yin, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

46

Refinement of the solution structure of the heparin-binding domain of vascular endothelial growth factor using residual dipolar couplings

Melissa E. Stauffer, Nicholas J. Skelton, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

47

Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity

Okamoto, Toru, Zobel, Kerry, Fedorova, Anna, Quan, Clifford, Yang, Hong, Fairbrother, Wayne J., Huang, David C. S., Smith, Brian J., Deshayes, Kurt, Czabotar, Peter E.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.26 MB

english, 2013

48

Characterization of ML-IAP protein stability and physiological role in vivo

Varfolomeev, Eugene, Moradi, Elham, Dynek, Jasmin N., Zha, Jiping, Fedorova, Anna V., Deshayes, Kurt, Fairbrother, Wayne J., Newton, Kim, Le Couter, Jennifer, Vucic, Domagoj

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

49

Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9

Holliday, Michael J., Ferrao, Ryan, de Leon Boenig, Gladys, Estevez, Alberto, Helgason, Elizabeth, Rohou, Alexis, Dueber, Erin C., Fairbrother, Wayne J.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 5.22 MB

english, 2018

50

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor

Wayne J. Fairbrother, Mark A. Champe, Hans W. Christinger, Bruce A. Keyt, Melissa A. Starovasnik

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 1.07 MB

english, 1997

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски